That knowledge could, subsequently, pave just how for novel therapeutic interventions for an illness that currently does not have any effective treatments.” “By better understanding the molecular and genetic mechanisms involved with microglia function, we’re in a far greater position to unravel the regulatory landscape that controls that function and plays a part in AD.
“Our study may be the largest human fresh-tissue microglia analysis up to now of genetic risk factors that may predispose you to definitely Alzheimer’s disease,” says senior author Panos Roussos, MD, Ph.D., Professor of Psychiatry, and Genetic and Genomic Sciences, at the Icahn School of Medicine at Mount Sinai and Director of the guts for Disease Neurogenomics. The team’s findings were published in Nature Genetics.ĭealing with fresh mind tissue harvested via biopsy or autopsy from 150 donors, researchers identified 21 candidate risk genes and highlighted one, SPI1, as a potential key regulator of microglia and AD risk. Mount Sinai researchers have achieved an unprecedented knowledge of the genetic and molecular machinery in human microgliaimmune cells that have a home in the brainthat could provide valuable insights into how they donate to the development and progression of Alzheimer’s disease (AD). 3:00-3:20pm: Steven W.PET scan of a mind with Alzheimer’s disease.2:40-3:00pm: Chung lab alumnus Sung-Yon Kim, Seoul National University, "Warm and Full: The Neurobiology of Innate Behavior".Session 4: Innovation & Invention || Moderator: Eric Grimson, Chancellor for Academic Advancement, MIT 1:45-2:05pm: Myriam Heiman, MIT, "Single-cell Dissection of the Human Cerebrovasculature".1:25-1:45pm: Choi lab Postdoctoral Associate, Jeong Tae Kwon, MIT.1:05-1:25pm: Tsai lab alumnus Joel Blanchard, Mount Sinai, "Investigating Mechanisms of Aging with Stem Cells".12:45-1:05pm: Bear lab alumnus Ben Auerbach, University of Illinois, "Bridging the Gap from Genes to Behavior in Autism Spectrum Disorders".Session 3: Brain Health & Disease || Moderator: Pam Belluck, Health and Science Writer, The New York Times 11:05-11:25am: Littleton lab alumnus Zachary Piccioli, Moderna, "Current Advantages and Future Prospects for mRNA Vaccines".10:45-11:05am: Nedivi Lab alumnus Jerry Chen, Boston University.Session 2: Development & Plasticity || Moderator: Morgan Sheng, Professor, Broad Institute of Harvard and MIT Miller, MIT, "One Journey from 20th to 21st Century Neuroscience" 9:50-10:10am: Susumu Tonegawa, MIT, "Memory Engram for Knowledge".9:30-9:50am: Wilson lab alumnus David Foster, UC Berkeley, "Do Animals have Imagination?".Session 1: Learning & Memory || Moderator: Tonegawa lab alumnus Steve Ramirez, Assistant Professor at Boston University Rafael Reif, and JPB Foundation President Barbara Picower. All registrants will be sent the livestream link via email one week prior to the event (with reminders the day prior and morning of the event). Please keep in mind that emails will be sent to the email address you use to register.įeaturing Institute Director Li-Huei Tsai , MIT President L. In-person in Singleton Auditorium (46-3002), located on the third floor of MIT Building 46 (43 Vassar St, Cambridge, MA 02139).This will be a hybrid event, with options to join both in-person and/or virtually. Please click here to register or enter into your search bar.
#Sinai imail registration#
This event is FREE and OPEN TO THE PUBLIC but registration is required. The symposium will feature a range of lay-friendly brain science talks from Picower Institute faculty and their alumni with opportunities to informally interact at lunch and at the reception that will follow the talks. On Septemwe will celebrate the 20th anniversary of The Picower Institute for Learning and Memory with an Exhibition Symposium - a day-long hybrid event highlighting "Two Decades of Discovery & Impact" since the launch of the Institute by a transformational gift from Barbara and Jeffry Picower. Join us in celebrating the Picower Institute for Learning and Memory's 20th Anniversary!
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